- Scientists have discovered a key signalling process in DNA repair
- They have used this process in the development of a drug to reverse ageing
- Trials on mice found that the pill repaired DNA damage after a week
- Nasa wants the new technology to protect its astronauts from solar radiation
Scientists have made a discovery that could lead to a revolutionary drug that actually reverses ageing.
The drug could help damaged DNA to miraculously repair and even protect Nasa astronauts on Mars by protecting them from solar radiation.
A team of researchers developed the drug after discovering a key signalling process in DNA repair and cell ageing.
Scientists have made a discovery that could lead to a revolutionary drug that actually reverses ageing. A team of researchers developed the drug after discovering a key signalling process in DNA repair and cell ageing
THE ANTI-AGEING DRUG TRIALS
The experiments in mice, from a team at the University of New South Wales, suggest a treatment is possible for DNA damage from ageing and radiation.
It is so promising it has attracted the attention of Nasa scientists in their quest to reach Mars.
While our cells can naturally repair DNA damage – such as damage caused by the sun – this ability declines with age.
The scientists identified that the call signalling molecule NAD+, which is naturally present in every cell in the body, has a key role in protein interactions that control DNA repair.
Treating mice with an NAD+ ‘booster’ called NMN improved their cells’ ability to repair DNA damage caused by radiation exposure or old age.
Human trials of NMN therapy will begin within six months.
During trials on mice, the team found that the drug directly repaired DNA damage caused by radiation exposure or old age.
‘The cells of the old mice were indistinguishable from the young mice after just one week of treatment,’ said lead author Professor David Sinclair.
Human trials of the pill will begin within six months.